| Player | Mat | Inns | No | Runs | Avg | HS | SR | 50s | Team |
| Graeme Smith | 12 | 12 | 2 | 364 | 36.40 | 89* | 127.27 | 3 | South Africa/Africa XI |
| Misbah-ul-Haq | 10 | 10 | 5 | 338 | 67.60 | 87* | 135.20 | 3 | Pakistan |
| Andrew Symonds | 13 | 10 | 4 | 337 | 56.16 | 85* | 170.20 | 2 | Australia |
| Paul Collingwood | 13 | 13 | 0 | 330 | 25.38 | 79 | 140.42 | 2 | England |
| Kevin Pietersen | 13 | 13 | 0 | 321 | 24.69 | 79 | 158.12 | 1 | England/ICC World XI |
| Ricky Ponting | 10 | 10 | 2 | 315 | 39.37 | 98* | 138.15 | 2 | Australia/ICC World XI |
| Shoaib Malik | 12 | 12 | 2 | 313 | 31.30 | 57 | 128.27 | 2 | Pakistan |
| Matthew Hayden | 9 | 9 | 3 | 308 | 51.33 | 73* | 143.92 | 4 | Australia/ICC World XI |
| Brendon McCullum | 15 | 15 | 2 | 299 | 23.00 | 45 | 121.54 | 0 | New Zealand |
| Gautam Gambhir | 9 | 8 | 0 | 299 | 37.37 | 75 | 128.32 | 4 | India |
| Adam Gilchrist | 13 | 13 | 1 | 272 | 22.66 | 48 | 141.66 | 0 | Australia/ICC World XI |
| Sanath Jayasuriya | 7 | 7 | 1 | 246 | 41.00 | 88 | 165.10 | 3 | Sri Lanka/Asian XI |
| Jacob Oram | 9 | 8 | 3 | 242 | 48.40 | 66* | 164.62 | 2 | New Zealand |
| Scott Styris | 13 | 12 | 0 | 241 | 20.08 | 66 | 116.99 | 1 | New Zealand |
| Owais Shah | 9 | 9 | 1 | 235 | 29.37 | 55* | 135.05 | 1 | England |
| Younis Khan | 12 | 11 | 0 | 223 | 20.27 | 51 | 126.70 | 1 | Pakistan |
| Aftab Ahmed | 9 | 9 | 1 | 215 | 26.87 | 62* | 133.54 | 1 | Bangladesh |
| Justin Kemp | 8 | 7 | 3 | 203 | 50.75 | 89* | 126.87 | 1 | South Africa/Africa XI |
| Imran Nazir | 10 | 9 | 1 | 201 | 25.12 | 59 | 150.00 | 1 | Pakistan |
| Albie Morkel | 11 | 8 | 1 | 196 | 28.00 | 43 | 133.33 | 0 | South Africa |
| Chris Gayle | 5 | 5 | 0 | 193 | 38.60 | 117 | 164.95 | 1 | West Indies/ICC World XI |
| Craig McMillan | 8 | 7 | 1 | 187 | 31.16 | 57 | 159.82 | 1 | New Zealand |
| Herschelle Gibbs | 9 | 9 | 1 | 182 | 22.75 | 90* | 135.82 | 2 | South Africa |
| Mohammad Hafeez | 9 | 9 | 0 | 182 | 20.22 | 46 | 122.14 | 0 | Pakistan |
| Yuvraj Singh | 7 | 6 | 1 | 179 | 35.80 | 70 | 177.22 | 2 | India |
| Mohammad Nazimuddin | 7 | 7 | 0 | 178 | 25.42 | 81 | 112.65 | 1 | Bangladesh |
| Lou Vincent | 9 | 9 | 0 | 174 | 19.33 | 42 | 100.00 | 0 | New Zealand |
| Virender Sehwag | 9 | 8 | 0 | 172 | 21.50 | 68 | 130.30 | 1 | India/Asian XI |
| MS Dhoni | 10 | 9 | 2 | 172 | 24.57 | 45 | 111.68 | 0 | India |
| Ross Taylor | 12 | 11 | 1 | 171 | 17.10 | 62 | 126.66 | 1 | New Zealand |
| Mahela Jayawardene | 8 | 8 | 2 | 170 | 28.33 | 65 | 149.12 | 1 | Sri Lanka/Asian XI |
| Shahid Afridi | 11 | 10 | 0 | 168 | 16.80 | 39 | 169.69 | 0 | Pakistan/ICC World XI/Asian XI |
| Marcus Trescothick | 3 | 3 | 0 | 166 | 55.33 | 72 | 126.71 | 2 | England |
| Devon Smith | 5 | 5 | 0 | 166 | 33.20 | 61 | 123.88 | 2 | West Indies |
| Robin Uthappa | 9 | 8 | 0 | 149 | 18.62 | 50 | 115.50 | 1 | India |
| Michael Clarke | 13 | 10 | 3 | 147 | 21.00 | 37* | 126.72 | 0 | Australia |
| Mohammad Ashraful | 8 | 8 | 0 | 143 | 17.87 | 61 | 172.28 | 1 | Bangladesh/Asian XI |
| Kumar Sangakkara | 8 | 7 | 0 | 138 | 19.71 | 30 | 106.15 | 0 | Sri Lanka/Asian XI |
| Mike Hussey | 12 | 7 | 1 | 137 | 22.83 | 37 | 129.24 | 0 | Australia |
| Mark Boucher | 9 | 7 | 0 | 134 | 19.14 | 36 | 89.93 | 0 | South Africa/Africa XI |
| Shivnarine Chanderpaul | 6 | 6 | 1 | 133 | 26.60 | 41 | 102.30 | 0 | West Indies |
| AB de Villiers | 11 | 10 | 3 | 133 | 19.00 | 52* | 109.01 | 1 | South Africa/Africa XI |
| Marlon Samuels | 6 | 6 | 0 | 131 | 21.83 | 51 | 177.02 | 1 | West Indies |
| Damien Martyn | 4 | 4 | 0 | 120 | 30.00 | 96 | 162.16 | 1 | Australia |
| Peter Fulton | 9 | 9 | 1 | 117 | 14.62 | 25 | 100.00 | 0 | New Zealand |
| Matt Prior | 5 | 5 | 0 | 116 | 23.20 | 32 | 128.88 | 0 | England |
| Upul Tharanga | 8 | 8 | 0 | 114 | 14.25 | 37 | 116.32 | 0 | Sri Lanka |
| Darren Maddy | 4 | 4 | 0 | 113 | 28.25 | 50 | 141.25 | 1 | England |
| Brendan Taylor | 3 | 3 | 1 | 112 | 56.00 | 60* | 127.27 | 1 | Zimbabwe |
| Stephen Fleming | 5 | 5 | 0 | 110 | 22.00 | 38 | 129.41 | 0 | New Zealand/ICC World XI |