| Player | Mat | Balls | Runs | Wkts | Best | Avge | Econ | SR | 4 Wkt | 5 Wkt |
| Shaun Pollock | 303 | 15712 | 9631 | 393 | 6/35 | 24.50 | 3.67 | 39.97 | 12 | 5 |
| Allan Donald | 164 | 8561 | 5926 | 272 | 6/23 | 21.78 | 4.15 | 31.47 | 11 | 2 |
| Makhaya Ntini | 165 | 8291 | 6177 | 256 | 6/22 | 24.12 | 4.47 | 32.38 | 8 | 4 |
| Jacques Kallis | 274 | 9388 | 7536 | 239 | 5/30 | 31.53 | 4.81 | 39.28 | 2 | 2 |
| Lance Klusener | 171 | 7336 | 5751 | 192 | 6/49 | 29.95 | 4.70 | 38.20 | 1 | 6 |
| Hansie Cronje | 188 | 5357 | 3966 | 114 | 5/32 | 34.78 | 4.44 | 46.99 | 1 | 1 |
| Andre Nel | 76 | 3712 | 2857 | 106 | 5/45 | 26.95 | 4.61 | 35.01 | 3 | 1 |
| Nicky Boje | 115 | 4541 | 3415 | 96 | 5/21 | 35.57 | 4.51 | 47.30 | 2 | 1 |
| Andrew Hall | 88 | 3341 | 2515 | 95 | 5/18 | 26.47 | 4.51 | 35.16 | 3 | 1 |
| Fanie de Villiers | 83 | 4422 | 2636 | 95 | 4/27 | 27.74 | 3.57 | 46.54 | 2 | 0 |
| Charl Langeveldt | 58 | 2811 | 2334 | 82 | 5/39 | 28.46 | 4.98 | 34.28 | 1 | 2 |
| Craig Matthews | 56 | 3003 | 1975 | 79 | 4/10 | 25.00 | 3.94 | 38.01 | 3 | 0 |
| Pat Symcox | 80 | 3991 | 2762 | 72 | 4/28 | 38.36 | 4.15 | 55.43 | 1 | 0 |
| Brian McMillan | 78 | 3623 | 2589 | 70 | 4/32 | 36.98 | 4.28 | 51.75 | 1 | 0 |
| Roger Telemachus | 37 | 1918 | 1565 | 56 | 4/43 | 27.94 | 4.89 | 34.25 | 1 | 0 |
| Steve Elworthy | 39 | 1702 | 1235 | 44 | 3/17 | 28.06 | 4.35 | 38.68 | 0 | 0 |
| Richard Snell | 42 | 2095 | 1574 | 44 | 5/40 | 35.77 | 4.50 | 47.61 | 2 | 1 |
