| Player | Mat | Inns | NO | Runs | Avg | HS | SR | 50s | 100s | 0s | Gold 0s | 4s | 6s | ct | st |
| Jacques Kallis | 274 | 260 | 49 | 9541 | 45.21 | 139 | 71.35 | 65 | 16 | 11 | 4 | 745 | 114 | 101 | 0 |
| Boeta Dippenaar | 107 | 95 | 14 | 3421 | 42.23 | 125 | 67.78 | 26 | 4 | 3 | 1 | 334 | 16 | 36 | 0 |
| Graeme Smith | 133 | 131 | 9 | 5016 | 41.11 | 134 | 81.80 | 36 | 7 | 6 | 2 | 586 | 31 | 71 | 0 |
| Lance Klusener | 171 | 137 | 50 | 3576 | 41.10 | 103 | 89.91 | 19 | 2 | 8 | 5 | 293 | 76 | 35 | 0 |
| Gary Kirsten | 185 | 185 | 19 | 6798 | 40.95 | 188 | 72.04 | 45 | 13 | 9 | 2 | 659 | 20 | 61 | 1 |
| Hansie Cronje | 188 | 175 | 31 | 5565 | 38.64 | 112 | 76.48 | 39 | 2 | 7 | 1 | 366 | 94 | 73 | 0 |
| Neil McKenzie | 59 | 51 | 10 | 1580 | 38.53 | 131 | 69.69 | 9 | 2 | 1 | 1 | 133 | 8 | 19 | 0 |
| Peter Kirsten | 40 | 40 | 6 | 1293 | 38.02 | 97 | 56.02 | 9 | 0 | 0 | 0 | 90 | 8 | 11 | 0 |
| AB de Villiers | 67 | 64 | 7 | 2147 | 37.66 | 146 | 85.26 | 13 | 3 | 5 | 0 | 240 | 39 | 42 | 0 |
| Herschelle Gibbs | 227 | 220 | 16 | 7453 | 36.53 | 175 | 83.08 | 34 | 20 | 16 | 6 | 849 | 121 | 98 | 0 |
| Jean-Paul Duminy | 28 | 24 | 7 | 618 | 36.35 | 79 | 73.30 | 3 | 0 | 1 | 2 | 47 | 5 | 8 | 0 |
| Jacques Rudolph | 45 | 39 | 6 | 1174 | 35.57 | 81 | 68.05 | 7 | 0 | 0 | 0 | 109 | 5 | 11 | 0 |
| Jonty Rhodes | 245 | 220 | 51 | 5935 | 35.11 | 121 | 80.91 | 33 | 2 | 9 | 3 | 392 | 47 | 105 | 0 |
| Ashwell Prince | 52 | 41 | 12 | 1018 | 35.10 | 89 | 67.77 | 3 | 0 | 3 | 1 | 77 | 4 | 26 | 0 |
| Kepler Wessels | 109 | 105 | 7 | 3367 | 34.35 | 107 | 55.28 | 26 | 1 | 0 | 0 | 263 | 2 | 49 | 0 |
| Adrian Kuiper | 25 | 23 | 7 | 539 | 33.68 | 63 | 81.41 | 3 | 0 | 0 | 0 | 37 | 11 | 3 | 0 |
| Daryll Cullinan | 138 | 133 | 16 | 3860 | 32.99 | 124 | 70.28 | 23 | 3 | 10 | 0 | 298 | 33 | 62 | 0 |
| Justin Kemp | 85 | 66 | 18 | 1512 | 31.50 | 100 | 83.12 | 10 | 1 | 4 | 2 | 98 | 60 | 33 | 0 |
| Andrew Hudson | 89 | 88 | 1 | 2559 | 29.41 | 161 | 64.55 | 18 | 2 | 3 | 3 | 278 | 15 | 18 | 0 |
| Mark Boucher | 263 | 193 | 48 | 4203 | 28.98 | 147 | 84.12 | 25 | 1 | 8 | 6 | 320 | 73 | 368 | 18 |
| Mike Rindel | 22 | 22 | 1 | 575 | 27.38 | 106 | 66.86 | 2 | 1 | 1 | 0 | 56 | 8 | 0 | |
| Nicky Boje | 115 | 71 | 18 | 1414 | 26.67 | 129 | 88.70 | 4 | 2 | 1 | 1 | 135 | 13 | 33 | 0 |
| Shaun Pollock | 303 | 205 | 72 | 3519 | 26.45 | 130 | 86.69 | 14 | 1 | 15 | 5 | 248 | 58 | 108 | 0 |
| Dave Callaghan | 29 | 25 | 6 | 493 | 25.94 | 169 | 67.90 | 0 | 1 | 1 | 1 | 43 | 5 | 6 | 0 |
| Brian McMillan | 78 | 52 | 16 | 841 | 23.36 | 127 | 73.19 | 0 | 1 | 2 | 1 | 55 | 7 | 42 | 0 |
| Andrew Hall | 88 | 56 | 13 | 905 | 21.04 | 81 | 75.04 | 3 | 0 | 1 | 4 | 90 | 10 | 29 | 0 |
| Dave Richardson | 122 | 77 | 33 | 868 | 19.72 | 53 | 66.87 | 1 | 0 | 5 | 1 | 33 | 1 | 148 | 17 |
| Dale Benkenstein | 23 | 20 | 3 | 305 | 17.94 | 69 | 65.87 | 1 | 0 | 3 | 0 | 20 | 0 | 3 | 0 |
| Pat Symcox | 80 | 54 | 13 | 694 | 16.92 | 61 | 83.61 | 3 | 0 | 1 | 5 | 48 | 22 | 23 | 0 |
| Richard Snell | 42 | 28 | 8 | 322 | 16.10 | 63 | 97.57 | 2 | 0 | 1 | 0 | 20 | 4 | 7 | 0 |
| Derek Crookes | 32 | 23 | 3 | 296 | 14.80 | 54 | 71.84 | 1 | 0 | 2 | 1 | 20 | 5 | 20 | 0 |
| Andre Nel | 76 | 20 | 12 | 104 | 13.00 | 30 | 73.23 | 0 | 0 | 1 | 1 | 11 | 3 | 21 | 0 |
| Craig Matthews | 56 | 22 | 9 | 141 | 10.84 | 26 | 69.80 | 0 | 0 | 2 | 1 | 5 | 2 | 10 | 0 |
| Makhaya Ntini | 165 | 42 | 21 | 186 | 8.85 | 42 | 66.66 | 0 | 0 | 5 | 3 | 16 | 5 | 30 | 0 |
| Fanie de Villiers | 83 | 36 | 15 | 170 | 8.09 | 20 | 77.98 | 0 | 0 | 2 | 5 | 13 | 2 | 15 | 0 |
| Allan Donald | 164 | 40 | 18 | 95 | 4.31 | 13 | 34.05 | 0 | 0 | 7 | 5 | 2 | 0 | 28 | 0 |