| Player | Total Fours | Career Runs | Team |
| Graeme Smith | 52 | 364 | South Africa / Africa XI |
| Matthew Hayden | 37 | 308 | Australia / ICC World XI |
| Kevin Pietersen | 34 | 321 | England / ICC World XI |
| Gautam Gambhir | 34 | 299 | India |
| Andrew Symonds | 32 | 317 | Australia |
| Ricky Ponting | 32 | 315 | Australia / ICC World XI |
| Sanath Jayasuriya | 31 | 246 | Sri Lanka / Asian XI |
| Brendon McCullum | 30 | 299 | New Zealand |
| Adam Gilchrist | 27 | 272 | Australia / ICC World XI |
| Aftab Ahmed | 25 | 212 | Bangladesh |
| Herschelle Gibbs | 24 | 182 | South Africa |
| Marcus Trescothick | 23 | 166 | England |
| Paul Collingwood | 23 | 330 | England |
| Mohammad Hafeez | 23 | 182 | Pakistan |
| Stephen Fleming | 20 | 110 | New Zealand / ICC World XI |
| Jacob Oram | 20 | 242 | New Zealand |
| Shoaib Malik | 20 | 278 | Pakistan |
| Misbah-ul-Haq | 20 | 251 | Pakistan |
| Virender Sehwag | 19 | 172 | India / Asian XI |
| Devon Smith | 19 | 166 | West Indies |
| Scott Styris | 18 | 241 | New Zealand |
| Kumar Sangakkara | 18 | 138 | Sri Lanka / Asian XI |
| Chris Gayle | 18 | 193 | West Indies / ICC World XI |
| Imran Nazir | 18 | 201 | Pakistan |
| Owais Shah | 18 | 235 | England |
| Lou Vincent | 17 | 174 | New Zealand |
| Justin Kemp | 17 | 203 | South Africa / Africa XI |
| Mahela Jayawardene | 17 | 170 | Sri Lanka / Asian XI |
| Mark Boucher | 14 | 134 | South Africa / Africa XI |
| AB de Villiers | 14 | 133 | South Africa / Africa XI |
| Shahid Afridi | 14 | 158 | Pakistan / ICC World XI |
| Mohammad Ashraful | 14 | 130 | Bangladesh / Asian XI |
| Robin Uthappa | 14 | 149 | India |
| Mohammad Nazimuddin | 13 | 136 | Bangladesh |
| MS Dhoni | 13 | 172 | India |
| Shivnarine Chanderpaul | 12 | 133 | West Indies |
| Darren Maddy | 12 | 113 | England |
| Damien Martyn | 11 | 120 | Australia |
| Albie Morkel | 11 | 196 | South Africa |
| Younis Khan | 11 | 176 | Pakistan |
| Yuvraj Singh | 11 | 199 | India |
| Vikram Solanki | 10 | 76 | England |
| Upul Tharanga | 10 | 114 | Sri Lanka |
| Denesh Ramdin | 10 | 82 | West Indies |
| Salman Butt | 10 | 106 | Pakistan |
| Vusimuzi Sibanda | 10 | 52 | Zimbabwe |
| Rohit Sharma | 10 | 96 | India |
| Dinesh Karthik | 9 | 67 | India |
| Saqibul Hasan | 9 | 93 | Bangladesh |
| Brendan Taylor | 9 | 112 | Zimbabwe |
