| Player | Total Fours | Career Runs | Team |
| Brian Lara | 1559 | 11953 | West Indies / ICC World XI |
| Sachin Tendulkar | 1552 | 11782 | India |
| Rahul Dravid | 1245 | 9920 | India / Asian XI |
| Steve Waugh | 1175 | 10927 | Australia |
| Allan Border | 1161 | 11174 | Australia |
| Alec Stewart | 1121 | 8463 | England |
| Inzamam-ul-Haq | 1105 | 8830 | Pakistan / Asian XI |
| Ricky Ponting | 1097 | 9776 | Australia / ICC World XI |
| Graham Gooch | 1079 | 8900 | England |
| Jacques Kallis | 1062 | 9477 | South Africa / ICC World XI |
| Sir Viv Richards | 1051 | 8540 | West Indies |
| Sunny Gavaskar | 1016 | 10122 | India |
| Matthew Hayden | 990 | 8242 | Australia / ICC World XI |
| David Gower | 979 | 8231 | England |
| Gary Kirsten | 922 | 7289 | South Africa |
| Justin Langer | 912 | 7696 | Australia |
| Sanath Jayasuriya | 910 | 6973 | Sri Lanka / Asian XI |
| Mike Atherton | 904 | 7728 | England |
| Stephen Fleming | 899 | 7047 | New Zealand / ICC World XI |
| Herschelle Gibbs | 887 | 6167 | South Africa |
| Mahela Jayawardene | 887 | 7271 | Sri Lanka / Asian XI |
| Gordon Greenidge | 884 | 7558 | West Indies |
| Mohammad Yousuf | 869 | 6770 | Pakistan / Asian XI |
| Shivnarine Chanderpaul | 859 | 7429 | West Indies |
| Mark Waugh | 844 | 8029 | Australia |
| Sourav Ganguly | 839 | 6581 | India / Asian XI |
| Marcus Trescothick | 831 | 5825 | England |
| Desmond Haynes | 830 | 7487 | West Indies |
| David Boon | 822 | 7422 | Australia |
| Kumar Sangakkara | 810 | 6032 | Sri Lanka / Asian XI |
| Javed Miandad | 809 | 8832 | Pakistan |
| Graham Thorpe | 778 | 6744 | England |
| VVS Laxman | 777 | 5658 | India |
| Geoff Boycott | 771 | 8114 | England |
| Richie Richardson | 761 | 5949 | West Indies |
| Clive Lloyd | 758 | 7515 | West Indies |
| Aravinda de Silva | 756 | 6361 | Sri Lanka |
| Greg Chappell | 755 | 7110 | Australia |
| Colin Cowdrey | 752 | 7624 | England |
| Nasser Hussain | 734 | 5764 | England |
| Chris Gayle | 730 | 4658 | West Indies / ICC World XI |
| Mark Taylor | 727 | 7525 | Australia |
| Mohammad Azharuddin | 720 | 6215 | India |
| Garry Sobers | 719 | 8032 | West Indies |
| Michael Vaughan | 711 | 5473 | England |
| Marvan Atapattu | 685 | 5502 | Sri Lanka |
| Don Bradman | 681 | 6996 | Australia |
| Saleem Malik | 678 | 5768 | Pakistan |
| Adam Gilchrist | 677 | 5570 | Australia / ICC World XI |
| Graeme Smith | 677 | 5146 | South Africa / Africa XI |