| Runs | Players | Teams | Venue | Date |
| 1st | 235 | Gary Kirsten and Herschelle Gibbs | South Africa in India: 1st ODI, 1999/00 | Nehru Stadium, Kochi | 9 March 2000 |
| 2nd | 209 | Gary Kirsten and Neil McKenzie | Standard Bank Triangular Tournament: 8th Match, 2001/02 | Newlands, Cape Town | 22 October 2001 |
| 3rd | 238 | Hashim Amla and AB de Villiers | Pakistan in South Africa 2012/13 (3rd ODI) | Bidvest Wanderers Stadium, Johannesburg | 17th March 2013 |
| 4th | 232 | Daryll Cullinan and Jonty Rhodes | KCA Centenary Tournament: 2nd Match, 1996/97 | Gymkhana Club Ground, Nairobi | 29 September 1996 |
| 5th | 138 | Jonty Rhodes and Mark Boucher | VB Series: 11th Match, 2001/02 | W.A.C.A. Ground, Perth | 1 February 2002 |
| 6th | 137 | Hansie Cronje and Shaun Pollock | Standard Bank International One-Day Series: 5th Match, 1996/97 | New Wanderers Stadium, Johannesburg | 31 January 1997 |
| 7th | 114 | Herschelle Gibbs and Lance Klusener | South Africa in India: 5th ODI, 1999/00 | Vidarbha C.A. Ground, Nagpur | 19 March 2000 |
| 8th | 91 | Dale Benkenstein and Lance Klusener | West Indies in South Africa: 5th ODI, 1998/99 | Newlands, Cape Town | 2 February 1999 |
| 9th | 65 | Jacques Kallis and Dale Steyn | South Africa in India 2009/10 (1st ODI) | Sawai Mansingh Stadium, Jaipur | 21st February 2010 |
| 10th | 200 | Shaun Pollock and Morne Morkel | Afro-Asia Cup: 1st Match, 2007 | M.Chinnaswamy Stadium, Bangalore | 6 June 2007 |
