| Player | Total Fours | Career Runs | Team |
| Brendon McCullum | 176 | 1814 | New Zealand |
| Mahela Jayawardene | 145 | 1293 | Sri Lanka / Asian XI |
| Tillakaratne Dilshan | 129 | 1120 | Sri Lanka |
| Graeme Smith | 123 | 982 | South Africa / Africa XI |
| Kevin Pietersen | 119 | 1176 | England / ICC World XI |
| Mohammad Hafeez | 114 | 1013 | Pakistan |
| David Warner | 112 | 1206 | Australia |
| Kumar Sangakkara | 110 | 1080 | Sri Lanka / Asian XI |
| Gautam Gambhir | 109 | 932 | India |
| Martin Guptill | 101 | 1168 | New Zealand |
| Chris Gayle | 87 | 993 | West Indies / ICC World XI |
| Kamran Akmal | 82 | 849 | Pakistan |
| Eoin Morgan | 80 | 871 | Ireland |
| Sanath Jayasuriya | 76 | 629 | Sri Lanka / Asian XI |
| Suresh Raina | 76 | 840 | India |
| Jean-Paul Duminy | 76 | 952 | South Africa |
| Shane Watson | 74 | 980 | Australia |
| Shahid Afridi | 73 | 864 | Pakistan / ICC World XI |
| Shoaib Malik | 72 | 880 | Pakistan |
| Virat Kohli | 70 | 558 | India |
| Tamim Iqbal | 70 | 576 | Bangladesh |
| Umar Akmal | 67 | 874 | Pakistan |
| Salman Butt | 66 | 594 | Pakistan |
| William Porterfield | 61 | 475 | Ireland |
| Hamilton Masakadza | 61 | 708 | Zimbabwe |
| AB de Villiers | 61 | 818 | South Africa / Africa XI |
| Imran Nazir | 59 | 500 | Pakistan |
| Michael Hussey | 58 | 721 | Australia |
| Shakib Al Hasan | 58 | 528 | Bangladesh |
| Jacques Kallis | 56 | 666 | South Africa / ICC World XI |
| Ross Taylor | 55 | 876 | New Zealand |
| Johnson Charles | 54 | 401 | West Indies |
| Luke Wright | 54 | 649 | England |
| Paul Stirling | 52 | 415 | Ireland |
| Alex Hales | 52 | 524 | England |
| MS Dhoni | 51 | 748 | India |
| Mohammad Ashraful | 48 | 450 | Bangladesh / Asian XI |
| Craig Kieswetter | 47 | 526 | England |
| Misbah-ul-Haq | 45 | 788 | Pakistan |
| Herschelle Gibbs | 45 | 400 | South Africa |
| Yuvraj Singh | 45 | 791 | India |
| Chamu Chibhabha | 44 | 391 | Zimbabwe |
| Virender Sehwag | 43 | 394 | India / Asian XI |
| Jesse Ryder | 42 | 412 | New Zealand |
| Rohit Sharma | 42 | 531 | India |
| Cameron White | 41 | 712 | Australia |
| Ricky Ponting | 41 | 401 | Australia / ICC World XI |
| David Hussey | 41 | 756 | Australia |
| Lendl Simmons | 41 | 430 | West Indies |
| Mohammad Shahzad | 40 | 432 | Afghanistan |
