After revelling in the memory of one of my friend's drunken possum-kicking last night, I thought I'd make this thread where you can mention the funniest stories you know of people who have been temporarily affected by certain substances.
Another good one IMO from two nights ago was when my friend and I decided to microwave meat pies for dinner (we were at a campsite). While I was preparing them, my friend bit my arm, started laughing hysterically, ran around the kitchen and collapsed next to the door. I got milk out of the fridge to throw on him, but he whacked it out of my hand and it splattered all over another guy's pants. We left him to clean himself up and went back to our tent, where my friend's half-cooked pie was ruined when he smashed it on his face.